Active Studies Recruiting

Rheumatoid Arthritis and Anti-Inflammatory Diet - with the Division of Rheumatology

Enrollment: Currently Enrolling
Study Duration: 3 months
Requirements: Men or women, any age, with rheumatoid arthritis*

Dr. Guma from the Division of Rheumatology at UC San Diego, together with the Center for Integrative Nutrition and Research, is conducting a study of a 3-month long program to test nutritional changes for patients with rheumatoid arthritis. *Any patient with rheumatoid arthritis without food allergies can participate. There will be four, one-hour, face-to-face visits required. Participation will also involve education and support in the adoption of a healthy and nutritionally balanced anti-inflammatory diet. The program includes a detailed baseline orientation, expert nutrition counseling and education, and telephone coaching.

If you are interested in the study and would like further details, please contact the Nutrition Rheumatoid Arthritis Study Coordinator at z2manalo@health.ucsd.edu or call 858-822-3745. You may also review the study flyer here.

Ophthalmology and Diet – Shiley Eye Institute

Enrollment: Currently Enrolling
Study Duration: 12 months (6 months observation, 6 months active)
Requirements: Men or women ages 18-80 years with stable open angle glaucoma (OAG)*

Compensation: up to $225

Interested in Food as Medicine for Eye Health?

Glaucoma affects about 80 million people worldwide and is the leading cause of blindness. Presently, there is no cure, yet evidence suggests prevention and early treatment for glaucoma is successful with the use of food as medicine. Glaucoma presents as either progressive open angle glaucoma (POAG) or closed angle glaucoma. POAG is the most common, representing at least 90% of cases. Many characteristics of this condition, including high intraocular pressure (IOP), have been linked to systemic metabolic and cellular health and research is beginning to show evidence of influence by dietary modifications on outcomes related to glaucoma.

Shiley Eye Institute and the Krupp Center for Integrative Research (KCIR) are conducting a study to examine the health effects of a wholefoods, plant-based (WFPB) diet on the eyes.

What to Expect:

  • Learn basics of healthy cooking and try new therapeutic recipes  
  • Develop a deeper understanding of the energetics of food, cooking and eating 
  • Attend cooking classes and group meetings u Involve support person(s) in cooking classes, groups, shared meals, or whenever possible
  • Blood samples will be collected to have a better understanding of your DNA, diet and visual function
  • Various eye tests will be performed to have a better understanding of your current eye health

For more information about this study, including participation, please contact us at (858) 822-1643 or krupp-wellness@health.ucsd.edu.

*Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Integrative Prehabilitation Program for Patients Facing Surgery

Enrollment: Currently Enrolling
Study Duration: 3-5 months
Requirements: Men or women aged 18-75 years undergoing major abdominal surgery for gastrointestinal cancer*

Enrolled participants will participate in a three- to five-month integrative pre- and postoperative program inclusive of nutrition, exercise, and anxiety management. To qualify you must enroll in the study up to 3 months but no less than 4 weeks before surgery. Benefits of this study include working with a team of UC San Diego professionals: Mindfulness Coach, Registered Dietitian, and Exercise Physiologist!

Provided to you at no cost:

  • mindfulness sessions
  • dietary counseling
  • exercise consultations

If you are aged 18-75 years undergoing major abdominal surgery for gastrointestinal cancer and meet other eligibility criteria, you may qualify to participate!

If you are interested in the study and would like further information, please contact us at: 858-413-7728 or krupp-wellness@health.ucsd.edu.

*Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Evaluating the Effects of Magnesium on Arterial Compliance and Cerebral Blood Flow

Enrollment: Currently Enrolling
Study Duration: 12 weeks
Requirements: 

This feasibility study aims to examine whether 12 weeks of magnesium supplementation (450 mg magnesium citrate 3x day with food) might increase cerebral blood flow and reduce the stiffness of the medium-sized arteries in the brain of obese patients with metabolic syndrome. Blood and MRI were measured before and after the intervention. 

If you are interested in the study and would like further information, please contact us at: 858-249-6896 or krupp-wellness@health.ucsd.edu.

*Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Anti-Inflammatory Rich Diet in First Episode Psychosis

Enrollment: Currently Enrolling
Study Duration: 5 weeks
Requirements: 

The goal of the study is multi-facet: develop and test a diet intervention based on anti-inflammatory, wholesome foods using continuous feedback from early psychosis patients and their families; evaluate the feasibility, satisfaction, and adherence of a 5-week diet intervention in 12 patients with early psychosis and explore whether a 5-week adherence to an anti-inflammatory wholesome foods diet effects weight, metabolic parameters, biomarkers, symptoms of psychosis, and overall well-being. 

If you are interested in the study and would like further information, please contact us at: 619-543-7816 or krupp-wellness@health.ucsd.edu.

*Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Integrative Plant-Based Diet & Behavioral Interventions for Patients with Laryngopharyngeal Reflux

Enrollment: Currently Enrolling
Study Duration: 8 weeks
Requirements: 

This study explores an 8-week integrative nutrition and speech therapy program inclusive of a standard of care visits including one in-person speech therapy assessment and six telehealth visits with registered dietitians and SLPs. The intervention includes a Principal Investigator lead orientation video; counseling with dietitians and speech language therapists; two telehealth nutrition assessments; food journals and speech assessments. 

If you are interested in the study and would like further information, please contact us at: 858-249-6896 or krupp-wellness@health.ucsd.edu.

*Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Weight Management:  Dissemination and Implementation of Shared Medical Appointments at UC San Diego Health

Enrollment: Currently Enrolling
Study Duration: 6 months
Requirements: 

The UCSD Supervised Lifestyle and Integrative Medicine (SLIM) Program for the treatment of obesity is a virtual SMA program that has a curriculum based on USPSTF recommendations for intensive lifestyle change and meets the requirements of ITLC outlined in the American College of Lifestyle Medicine position statement on ITLC. It is run by the UC San Diego Center for Integrative Medicine, and in-person assessment visits take place at the UC San Diego Center for Weight Management. The program consists of 12 visits, covering all six pillars of Lifestyle Medicine. There are 2 pre-intervention visits for initial assessments and tailored recommendations and 2 follow-up assessments.

If you are interested in the study and would like further information, please contact us at: 858-413-7728 or krupp-wellness@health.ucsd.edu.

*Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Preoperative Flavanols Supplementation in Elderly Patients to Reduce Inflammatory Markers and Improve Mitochondrial Function

Enrollment: Currently Enrolling
Study Duration: 2 weeks
Requirements: over 50-year-old preoperative patients undergoing hip and/or knee replacement surgeries

Join Our Study on Anti-inflammatory Supplements for Surgery Preparation 

Are you scheduled for hip or knee replacement surgery? UC San Diego Krupp Center for Integrative Research invites you to participate in a research study exploring the potential benefits of a 2-week anti-inflammatory supplement program for patients preparing for surgery. 

About the Study 

Led by Dr. Byron Fergerson, Clinical Professor and Vice Chair of Anesthesiology at UCSD Health, this study will evaluate a flavanol-based supplement aimed at supporting recovery and overall health in patients 50 years or older preparing for hip or knee replacement surgery. 

Who can Participate? 

You may be eligible if you: 

  • Are age 50 years or older 
  • Live in San Diego County
  • Are scheduled for hip or knee replacement surgery

What Participation Involves 

As a participant, you will: 

  • 2 in-home blood draws and complete questionnaires as part of the study 
  • Keep a brief daily log of your supplement intake 
  • Take one 500 mg capsule of the supplement daily for 14 consecutive days 

Participant Benefits 

While direct health benefits cannot be guaranteed, the flavanol supplement may have anti-inflammatory effect and antioxidant effects. Other potential benefits include improvements in cognitive function, mood, and recovery following surgery. Participants who complete all the study requirements may receive up to $100 in compensation. 

How to Join 

Interested? Simply fill out our online screening form (delete if not using a form). Our study coordinator will reach out to you to confirm eligibility, discuss the study details, and answer any questions you may have.  

(OR) 

If you’re interested in joining or have questions about participating, please reach out to us: Phone: (619) 929-0828 or krupp-wellness@health.ucsd.edu.

*Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Time-Restricted and Healthy Eating in Hepatocellular Carcinoma

Enrollment: Currently Enrolling
Study Duration: 1 year
Requirements: 18 or older and are being treated for early to mid-stage liver cancer

Join Our Time-Restricted Eating Study for Liver Cancer Patients 

Are you currently being treated for early to mid-stage liver cancer? UC San Diego Krupp Center for Integrative Research invites you to participate in a research study investigating how time-restricted eating along with some dietary changes can improve liver function and overall health. 

About the Study 

We are exploring the potential benefits of following a time-restricted and healthy diet for six months, plus a 6-month follow-up period, could affect patients undergoing treatment for liver cancer. The study focuses on whether nightly fasting, combined with nutritional guidance, can improve liver health and recovery. 

Who Can Participate? 

You may be eligible if you: 

  • Are 18 years or older
  • Have a Body Mass Index (BMI) greater than 27kg/m2
  • Currently practice nightly fasting of less than 12 hours
  • Diagnosed with early or mid-stage liver cancer and are referred for liver-directed therapy 

What Participation Involves 

As a participant, you may: 

  • Receive nutritional counseling and health coaching support on nightly fasting along with the following components throughout the 12 months 
  • Wear a continuous glucose monitor and an accelerometer for a total of 2 weeks
  • Follow a whole food, plant-based diet eating plan 
  • Attend 4 clinic visits in La Jolla and completing assessments and questionnaires Our team will provide detailed information about the study requirements, including the assessments that are involved. 
  • Track your start- and end-eating times daily in the health tracker app, Guava 
  • Receive compensation for your participation 

Participant Benefits 

While direct health benefits cannot be guaranteed, prolonged nightly fasting could improve sleep, stabilize blood sugar, reduce inflammation, and enhance metabolic health. Eligible participants who complete all study visits and requirements may receive up to $200 in compensation. 

How to Join 

Interested? Simply fill out our online screening form (delete if not using a form). Our study coordinator will reach out to you to confirm eligibility, discuss the study details, and answer any questions you may have.  

(OR) 

If you’re interested in joining or have questions about participating, please reach out to us: Phone: (619) 929-0828 Email: krupp-wellness@health.ucsd.edu