The UC San Diego Krupp Center for Integrative Research is committed to contributing to the growing body of scientific research in the field of integrative medicine and health. We sponsor innovative integrative medicine approaches that show the greatest promise of bettering human health for the largest number of people at the lowest cost.

Research Focus Area

Mitigating Toxic Impact: The Role of Melatonin, Coenzyme Q10, and N-Acetylcysteine in Post-Exposure Protection

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On February 3, 2023, a train derailed in East Palestine, Ohio (EP), spilling multiple toxic chemicals from the derailed cars. On February 6, officials decided to “vent and burn” the chemicals, which greatly expanded both the number of toxic chemicals and the geographic reach of the toxic plume carried by prevailing winds. Many residents and first responders experienced a range of symptoms, prominently including irritant symptoms (burning eyes, nose, mouth, and skin), headaches, fatigue, bloody nose, and respiratory symptoms and conditions such as rhinitis, sinusitis, and new asthma.

The study aims to assess the mitigating toxic impact of Melatonin, Coenzyme Q10, and N-Acetylcysteine in Post-Exposure Protection.

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Mitigating Toxic Impact: The Role of Melatonin, Coenzyme Q10, and N-Acetylcysteine in Post-Exposure Protection

Randomized Controlled Trial (RCT) of a Nutritional Intervention for Endometriosis

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This study aims to determine whether increasing consumption of a Whole-Food Plant-Based (WFPB) diet can improve quality of life, pain, and inflammation in women with endometriosis. This study is open for recruitment.

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RCT of a Nutritional Intervention for Endometriosis

Osteopathic Manipulative Treatment in Newborns with Breastfeeding Difficulties

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This randomized, placebo-controlled study aims to determine improvements in breastfeeding difficulty of hospitalized newborns. This study is in development, and recruitment has not yet begun.

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Osteopathic Manipulative Treatment in Newborns with Breastfeeding Difficulties

Chinese Herbs for COVID-19 Treatment Randomized Trial

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A multi-centered, randomized, double-blinded, placebo-controlled clinical trial to evaluate the safety of mQFPD as a modified form of Qing Fei Pai Du Tang (a Chinese herbal formula that has widely been used in Asia for COVID-positive outpatients with mild-to-moderate symptoms).

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RCT of Chinese Herbs for COVID-19 Treatment

Weight Management: Dissemination and Implementation of Shared Medical Appointments at UC San Diego Health

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A 6-month virtual shared medical appointment (SMA) program for weight management based on intensive lifestyle change. Includes in-person assessments and covers all six pillars of Lifestyle Medicine through 12 group visits and personalized support.

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Weight Management: Dissemination and Implementation of Shared Medical Appointments at UC San Diego Health

Rheumatoid Arthritis and Anti-Inflammatory Diet Randomized Trial

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A 3-month study testing how nutritional changes impact rheumatoid arthritis. Participants attend four in-person visits and receive expert counseling, education, and coaching to adopt a healthy, anti-inflammatory diet.

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Rheumatoid Arthritis and Anti-Inflammatory Diet – with the Division of Rheumatology

Integrative Plant-Based Diet & Behavioral Interventions for Patients with Laryngopharyngeal Reflux

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An 8-week dietary intervention for patients with laryngopharyngeal reflux (LPR) included telehealth nutrition counseling, speech evaluation, and a customized nutrition protocol.

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Integrative Plant-Based Diet & Behavioral Interventions for Patients with Laryngopharyngeal Reflux